Curriculum Vitae

 

Jay I. Sandlow, MD

Department of Urology

University of Iowa Hospitals and Clinics

200 Hawkins Drive

Iowa City, IA 52242

Phone:  319-356-2421

Phone:  319-353-7035

Fax:  319-356-3900

 

Hyperlink to:  www.medicine.uiowa.edu/malefertility

 

 

Expertise and Research Interests

Our research centers around factors involved in spermatogenesis, specifically c-kit, a proto-oncogene important in germ cell migration and maturation. We initially studied c-kit expression in normal and subfertile men utilizing immunohistochemistry. We were able to demonstrate that c-kit is expressed in Leydig cells, Type A spermatogonia, and the acrosomal granules of round spermatids. We also found that c-kit expression is decreased in subfertile men. Immunohistochemistry of the c-kit ligand, stem cell factor (SCF) demonstrated expression in Leydig cells and Sertoli cells, but not in germ cells (1). We found that staining for SCF was greater in the testis of men with maturational arrest than in normal testis, and postulated that this may be due in part to decreased c-kit receptors. Our subsequent staining for c-kit receptor was consistent with this hypothesis(2).

Our future plans include further characterization of c-kit expression through Northern and Western blot analysis, electron microscopy, in situ hybridization, and embryo cultures. We hope to define the role of c-kit in germ cell migration and maturation inorder to attempt to better understand problems with these complex processes.

I am also interested in the effects of vasectomy from both aphysiologic and psychologic viewpoint. There have been several recent studies postulating that vasectomy may increase a man's chance of developing prostate cancer. Although there is not any solid biological evidence for this, these papers received quite
a bit of publicity. We surveyed 1500 U.S. urologists to find out whether these studies have affected the way they performed vasectomies. We determined that although almost all urologists did notfeel that these studies affected their pattern of vasectomy practice, over 25% have changed their protocol for screening men for prostate cancer by screening vasectomized men earlier than non-vasectomized men(3).

We are also planning on studying the psychological aspects of vasectomy by surveying men undergoingvasectomy. We postulate that for some men, having a vasectomy is a major life change, and this can lead to profound psychological effects. We plan to question men before and after their vasectomy to determine the effect, if any, upon these individuals.
1. Sandlow JI, Cohen MB, Sandra A: Expression of the c-kit ligand in human testicular tissue. Presented at the Society for Basic Urologic Research Annual Meeting: San Francisco, CA, May 1994.

2. Sandlow JI, Cohen MB, Sandra A: Expression of the c-kitproto- oncogene in testicular tissue. Submitted.

3. Sandlow JI, Kreder KJ: Urologists' Practice Patterns in Response to Reports of a Possible Link Between Vasectomy and Prostate Cancer. Presented at the American Society for Reproductive Medicine AnnualMeeting: Seattle, WA, October 1995.

 

 

Education

 

                1983                BS                   University of Illinois, Champaign-Urbana, IL

                1987                MD                 Rush Medical College, Chicago, IL

 

 

Postgraduate Education

 

                1987-89                   Residency, General Surgery                               University of Iowa, Iowa City, IA

 

                1989-93                   Residency, Urology                                             University of Iowa, Iowa City, IA

 

                1993-95                   Fellowship, Infertility, American                       University of Iowa, Iowa City, IA

                                                   Foundation for Urologic Disease

 

 

Academic Appointments

 

                1994-95           Associate                                      Department of Urology

                                                                                                University of Iowa, Iowa City, IA

 

                1995-               Assistant Professor                     Department of Urology

                                                                                                University of Iowa, Iowa City, IA

 

Certification and Licensure

 

                A.  Certification

                                1993        American Board of Urology                       Part I

                                1997        American Board of Urology                       Part II

 

                B.  Licensure

                                Iowa (3-1-90)                 Permanent                    

                                Illinois (2/27/97)            Permanent               

 

Professional Affiliations

 

                1988-1997               American Medical Association

                1988-1997               American Urological Association, Candidate Member

                1988-                       Johnson County Medical Society

                1988-                       Iowa Medical Society

                1993-                       American Society for Reproductive Medicine

                1994-1998               American College of Surgeons, Associate Fellow

                1994-                       Society for the Study of Male Reproduction

                1994-                       American Society of Andrology

                1995-                       Society for Male Reproduction and Urology

                1996-                       Sigma Xi Scientific Research Society

                1996-                       Society of University Urologists

1996-                                  Iowa Urologic Society

1997-                                  American Urological Association-Member

                1998                        American College of Surgeons-Fellow

 

 

Areas of Research Interest

 

            Growth factors in male infertility

            Vasectomy

            Hormonal aspects of male infertility

 

 

Current Projects

 

            C-kit receptor in male infertility

            Psychological aspects of vasectomy

            Effect of varix size on outcomes following varicocele repair

            Intratesticular testosterone levels in humans

            Zebrafish as a model of male infertility

 

 

Other Professional Activities

 

                1995-                       Reviewer, Journal of Urology

                1996-                       Reviewer, Urology

                1998-                       Reviewer, Journal of Andrology

                1998-                       Reviewer, Fertility and Sterility

               

Committees

 

                Departmental

 

                1995-                       Medical Education Committee

                1996-                       M3 Clerkship, Director

                1996-                       Electronic Medical Records Committee

1997-                                  Advisory Committee

1998-                                  Research Committee

 

                Hospital, College of Medicine, and University

 

1995-                                  Hospital Medical Records Subcommittee

1996-                                  College of Medicine Clerkship Directors Committee

                1998                        Short Stay/Recovery Observation Unit Process Improvement Team

                1998                        Computer-based Patient Record Task Force

                1998-                       Medical Education Committee

                1998-                       Medical Admissions Committee

 

                National

 

                1996-                       American Society of Andrology Education Policy Committee

                1996-1998               American Society of Andrology Student Affairs Committee

                1996-                       Society for Reproductive Medicine Abstract Committee

                1997-                       Society for Male Reproduction and Urology/Andrology Resident Training Committee

                1998                        NIH, Reproductive Endocrinology Section, Ad Hoc Grants Committee, Reviewer

1999-2001                      Society for the Study of Male Reproduction, Executive Committee, Member at Large

                1999-                       Young Leadership Committee-North Central Section of American Urological Association

                1999-                       Editorial & Awards Committee- North Central Section of American Urological Association

 

 

Financial Resources

 

                American Foundation for Urologic Disease.  The Role of Molecular Biology in Spermatogenesis:  A Study of the C-kit Proto-oncogene and Nerve Growth Factor.  July 1, 1993-June 30, 1995; $88,000.

 

                Rockefeller Foundation.  GA PS 9340/9401.  The Role of Molecular Biology in Spermatogenesis:  A Study of the C-kit Proto-oncogene.  January 1, 1994-December 31, 1995; $20,000.

 

                American Cancer Society IRG-IN122Q:  The Expression of C-kit in Testicular Cancer.  July 1, 1996-June 30, 1997; $15,000.

 

                Urology Endowment Fund:  The C-kit Receptor and Male Infertility.  January 1998-December 1998; $26,000.

 

                Merck Pharmaceuticals:  A Supportive, Prospective, Multicenter, Double-Blind, randomized Comparative Study to Evaluate the Safety, Tolerability and Efficacy of MK-0826 versus Ceftriaxone Sodium in the Treatment of Complicated Urinary Tract Infections in Adults.  October 1998-April 1999; $92,040.

 

                Sponsor, American Foundation for Urologic Disease, Huialiang Feng, PhD.  July 1998-June 2000; $92,000

 

                Zeneca Pharmaceuticals:  A Randomized, Bouble-Blind, Comparative Trial of Bicalutamide 150 mg versus Placebo in Combination with Castration as a Second-line Therapy for Patients with Asymptomatic Metastatic Prostate Cancer.

 

                Zeneca Pharmaceuticals:  A Randomized Double Blind Comparative Trial of Bicalutamide versus Placebo in Patients with Early Prostate Cancer.

 

 

Bibliography

 

Papers Published/In Press

 

1.                    Holinger PC, Holinger DP, Sandlow JI:  Violent deaths among children in the United States.  Pediatrician 12:11-19, 1985.

 

2.                    Bahnson R, Becich M, Ernstoff MS, Sandlow JI, Cohen MB, Williams RD:  Absence of immunohistochemical metallothionein staining in bladder cancer tumor specimens predicts response to neoadjuvant cisplatin, methotrexate and vinblastine chemotherapy.  J Urol 152:2272-2275, 1994.

 

3.                    Sandlow JI, Cohen MB, Robinson RA, Dreicer R, Williams, RD:  The use of DNA ploidy and p-glycoprotein expression as predictive factors of pathological response to CMV chemotherapy for bladder cancer.  Urology 43:787-791, 1994.

 

4.                    Sandlow JI, Donovan, JF:  Treatment of male factor infertility (letter).  New Engl J Med 330:1154, 1994.

 

5.                    Cooper CS, Sandlow JI:  Azoospermia in a 46,XX/47XXX phenotypic male.  Urology 48:947-948, 1996.

 

6.                    Sandlow JI, Kreder K:  A change in practice:  current urological practice in response to reports concerning vasectomy and prostate cancer.  Fertil Steril 66:281-284, 1996.

 

7.                    Sandlow JI, Feng HL, Cohen MB, Sandra A:  Expression of c-kit and its ligand, stem cell factor, in normal and subfertile human testicular tissue.  J Androl 17:403-408, 1996.

 

8.                    Sandlow JI, Donovan JF, Sparks AET, Syrop CH, Van Voorhis BJ, Stovall D:  Microsurgical epididymal sperm aspiration.  Iowa Med 86:367-368, 1996.

 

9.                    Feng HL, Sandlow JI, Sandra A:  Expression and function of the c-kit proto-oncogene protein in mouse sperm.  Biol Reprod 57:194-203, 1997.

 

10.                 Sandlow JI, Feng HL, Sandra A:  Localization and expression of the c-kit receptor protein in human and rodent testis.  Urology 49:494-500, 1997.

 

11.                 Feng HL, Sandlow JI, Sandra A:  The c-kit receptor and its possible signaling transduction pathway in mouse spermatozoa.  Mol Reprod Devel 49:31-326, 1998.

 

12.                 Sandlow JI, Sparks AET:  Evaluation of the male in couples seeking reproductive assistance:  going beyond the seminal fluid analysis.  Assist Reprod Rev 8:36-39, 1998.

 

13.                 Donovan JF, DiBaise M, Sparks AET, Kessler J, Sandlow JI:  Comparison of microscopic epididymal sperm aspiration and intracytoplasmic sperm injection/in-vitro fertilization with repeat microscopic reconstruction following vasectomy:  is second attempt vas reversal worth the effort?  Hum Reprod 13:387-393, 1998.

 

14.           Feng HL, Sandlow JI, Sparks AET, Sandra A, Zheng, LJ:  Decreased expression of the c-kit receptor is associated with increased apoptosis in subfertile human testes.  Fertil Steril 71:85-9, 1999.

 

15.           Sandlow JI, Feng HL, Zheng LJ, Sandra A:  Migration and ultrastructural localization of the c-kit receptor protein in spermatogenic cells and spermatozoa of the mouse.  J Urol 161:1676-1680, 1999.

 

16.                 Feng HL, Sandlow JI:  Development of immunocontraceptives-current status.  J Reprod Med 44:759-765, 1999.

 

17.                 Schrepferman CG, Lester D, Sandlow JI:  Testicular amyloid deposition as a cause of secondary azoospermia. Urology 55:145, 2000.

 

18.           Sandlow JI:  Shattering the myths of male infertility.  Postgrad Med 107:235-245, 2000.

 

 

Books/Chapters

 

1.                    Holinger PC, Sandlow JI:  Epidemiology of suicide; Epidemiology of homicide; Epidemiology of motor vehicle accidents; Epidemiology of total accidents; and Synthesis:  violent deaths in aggregate.  In Holinger PC (ed.):  Violent Deaths in the United States:  An Epidemiologic Study of Suicide, Homicide, and Accidents.  New York:  Guilford Press, 1987.

 

2.                    Sandlow JI, Winfield HN:  State of the Art:  Transurethral resection of the prostate.  In Caste“ada F, Smith A, Caste“ada-Zu“iga W (eds.):  Therapeutic Alternatives in the Management of Benign Prostatic Hyperplasia.  New York:  Thieme Medical Publishers, Inc., 1993.

 

3.                    Donovan, JF, Cooper C, Kwon ED, Sandlow JI, Sparks AET.:  Preservation of fertility in the testicular cancer patient:  considerations before and after cancer therapy.  In Schnorr D, Loening SA, Weissbach L (eds.):  Hoden-tumoren Testis Cancer.  Berlin:  Blackwell Wissenschafts-Verlag, 1995.

 

4.                    Kwon ED, Sandlow JI, Donovan JF:  Laparoscopic varix ligation.  In Sosa RE, Jenkins A, Albala DM, Perlmutter A (eds.):  Textbook of Endourology.  Philadelphia: WB Saunders, 1997.

 

5.                    Donovan, JF, Kwon, ED, Sandlow JI:  The laparoscopic varix ligation.  In Marshall, FF (ed):  Textbook of Operative Urology.  Philadelphia:  WB Saunders, 1996.

 

6.                    Williams RD, Sandlow JI:  Surgery of the Seminal Vesicles.  In Walsh PC, Retik AB, Wein AJ, Vaughan ED, Jr. (eds.):  Campbell’s Urology, 7th ed.  Philadelphia:  WB Saunders, 1997.

 

7.                    Sandlow JI, Williams RD:  Anatomic and surgical considerations in radical nephrectomy.  In Droller MJ (ed.):  Atlas of the Urologic Clinics of North America.  Philadelphia:  WB Saunders, 1998.

 

 

Abstracts

 

1.                    Sandlow JI, Winfield HN, Loening SA:  Does extracorporeal shock wave lithotripsy augment stone recurrence?  J Urol 141:407A, no. 960, 1989.

 

2.                    Sandlow JI, Winfield HN, Loening SA:  Blood pressure changes in patients treated with repeated extracorporeal shock wave lithotripsy.  J Urol 141:242A, no. 290, 1989.

 

3.                    Sandlow JI, Winfield HN, Loening SA, Fallon B:  Comparison of treatment alternatives for complicated renal calculi.  J Urol 143:270A, no. 328, 1990.

 

4.                    Sandlow JI, Johnson PA, Sandra A:  b-Nerve growth factor expression in normal mouse testis.  J Urol 151:466A, no. 955, 1994.

 

5.                    Rashid TM, Winfield HN, Lund GO, Troxel SA, Sandlow JI, Donovan JF:  Comparative financial analysis of laparoscopic versus open varix ligation for men with clinically significant varicoceles.  J Urol 151:310A, no. 331, 1994.

 

6.                    Snyder OB, Feng HL, Sandlow JI, Sandra A:  Expression of the c-kit proto-oncogene in the type A spermatogonia cell line.  Proceedings, Society for Basic Urologic Research Annual Meeting; December 1996.

 

7.                    Feng HL, Sandlow JI, Sandra A:  Expression and function of the c-kit proto-oncogene protein in mouse sperm.  Biol Reprod 54(suppl 1):60, no. 17, 1996.

 

8.                    Sandlow JI, Feng HL:  Expression of the c-kit receptor in spermatogenic cells and normal sperm.  J Androl 17(suppl):P-24, no. 6, 1996.

 

9.                    Sandlow JI, Donovan JF, Sparks AET:  Evaluation of the male partner in couples undergoing assisted reproductive techniques.  Fertil Steril 66(suppl):S229, no. P-292, 1996.

 

10.                 Sandlow JI, Feng HL, Sandra A:  Localization and function of the c-kit receptors in testis and sperm.  Fertil Steril 66(suppl):S203, no. P-237, 1996.

 

11.                 Feng HL, Sandlow JI, Sandra A:  Localization of intracellular calcium and its possible role during spermatogenesis and sperm capacitation in the hamster.  Theriogenology 47:256, 1997.

 

12.                 Donovan JF, DiBaise M, Sparks AE, Kessler JA, Sandlow JI:  Is vas reconstruction worth the effort?  Comparison of repeat microscopic reconstruction of vas following failed vasectomy reversal and advanced reproductive techniques.  Fertil Steril 68(supp):S-35, no. O-069, 1997.

 

13.                 Feng HL, Sandlow JI, Sandra A:  Presence of the c-kit receptor and its possible signaling transduction pathway in mouse sperm.  Biol Reprod 56(supp):205, no. 490, 1997.

 

14.                 Sandlow JI, Feng HL, Sandra A:  Ultrastructural location of the c-kit receptor protein during mouse spermatogenesis.  Biol Reprod 56(supp):217, no. 540, 1997.

 

15.                 Zenni MK, Sandlow JI, Sparks AET, Donovan JF,:  The effect of varicocelectomy on strict morphology in men with male factor subfertility.  J Urol 157:170, No. 657, 1997.

 

16.                 Snyder OB, Feng HL, Sandlow JI, Sandra A:  Expression of the c-kit proto-oncogene in the type A spermatogonia cell line, GC-1.  J Urol 157:449, no. 1755, 1997.

 

17.                 Kramolowsky EV, Wood NL, Donovan JF, Sandlow JI:  Randomized comparison of open versus laparoscopic varix ligation for the treatment of infertility.  J Urol 157(4):143, no. 561, 1997.

 

14.                 Feng HL, Tan EQ, Zheng LJ, Bateman MJ, Sandlow JI, Eddy EM, Sandra A:  Expression of HSP-70, estrogen, and progesterone receptors in normal and subfertile human testicular tissue.  Theriogeneology 49:370, 1998.

 

15.                 Sandlow JI, Feng HL, Bateman MJ, Zheng LJ, Sandra A:  Expression of the c-kit receptor and apoptosis in the normal and subfertile human testes. Theriogeneology 49:372, 1998.

 

18.                 Snyder OB, Sandlow JI, Zenni MK, Donovan JF, Sparks AET:  Varix size correlates with improvement in total motile sperm/ejaculate and pregnancy rates.  J Urol 159:203, no. 784, 1998.

 

19.                 Feng HL, Sandlow JI, Bateman MJ, Zheng LJ, Sandra A:  Decreased expression of the c-kit receptor is associated with increased apoptosis in subfertile human testes. Fertil Steril 70 (supp):S81, no. O-219, 1998.

 

20.           Sandlow JI, Feng HL, Sparks AET, Sandra A:  Altered expression of the c-kit receptor in the sperm of subfertile men. Fertil Steril 70 (supp): S271, no. P-464, 1998.

 

21.           Sandlow JI, Westefeld JS, Maples M, Scheel KS:  The psychological correlates of vasectomy.  Fertil Steril 72 (supp), S46, no. O-236, 1999.

 

22.           Matkov TG, Levine LA, Zenni M, Sandlow JI:  Pre-operative semen analysis as a predictor of seminal improvement and pregnancy rates following varicocelectomy.  Fertil Steril 72 (supp), S84, no. O-220, 1999.

 

23.           Sandlow JI, Westefeld JS, Maples M, Scheel KS: Men’s concerns prior to vasectomy.  J Urol (in press).

 

24.           Schrepferman CG, Sandlow JI, Sparks AET:  Need for sperm retrieval and cryopreservation at the time of vasectomy reversal.  J Urol (in press).

 

25.           Westefeld JS, Sandlow JI, Maples MR, Scheel K. Psychological variables and vasectomy.  Annual Meeting of American Psychological Association, Washington, D.C., August 2000.

 

 

Presentations

 

1.                    Sandlow JI, Winfield HN, Loening SA:  Recurrent renal calculus formation following ESWL.  American Urological Association North Central Section Annual Meeting, Orlando, FL.  November 1988.

 

2.                    Sandlow JI, Winfield HN, Loening SA:  Blood pressure changes in patients treated with repeated extracorporeal shock waves.  American Urological Association North Central Section Annual Meeting, Orlando, FL.  November 1988.

 

3.                    Sandlow JI, Winfield HN:  Percutaneous nephrolithotripsy—the Iowa experience.  American Urological Association North Central Section Annual Meeting, Chicago, IL.  September 1989.

 

4.                    Sandlow JI:  Comparison of treatment alternatives for complicated renal calculi.  Texas Genitourinary Surgeon’s Annual Meeting, Iowa City, IA.  April 1990

 

5.                    Sandlow JI:  Zinc concentrations in the Dunning tumor.  Department of Urology—Iowa Friday, University of Iowa College of Medicine.  September 1990.

 

6.                    Sandlow JI:  Dynamics of zinc/androgen interactions in the Dunning tumor model of prostate cancer.  Continuing Medical Education Seminar:  University of Iowa College of Medicine.  May 1991.

 

7.                    Sandlow JI, Heidger PM, Lubaroff DM:  Stromal and epithelial zinc concentrations in the Dunning prostatic adenocarcinoma.  Association of American Anatomists Annual Meeting, Chicago, IL.  October 1991.

 

8.                    Sandlow JI, Loening SA:  Treatment of complicated renal stones.  Medical Outlook for Urologists (audio tape) vol. 5, no. 1, 1991.

 

9.                    Sandlow JI, Heidger PM, Lubaroff DM:  Dynamics of zinc/androgen interactions in the Dunning tumor model of CaP.  American Urological Association North Central Section Annual Meeting, Scottsdale, AZ.  November 1991.

 

10.                 Sandlow JI, Cohen MB, Robinson RA, Williams RD:  The use of flow cytometry in a predictor of response to neoadjuvant chemotherapy for bladder cancer.  American Urological Association North Central Section Annual Meeting, Scottsdale, AZ.  November 1991.

 

11.                 Sandlow JI, Cohen MB, Sandra A:  Expression of the c-kit ligand in human testicular tissue.  National Student Research Forum, Galveston, TX.  April 1994.

 

12.                 Sandlow JI, Cohen MB, Sandra A:  Expression of the c-kit ligand in human testicular tissue.  Society for Basic Urologic Research Annual Meeting, San Francisco, CA.  May 1994.

 

13.                 Rashid TM, Winfield HN, Lund GO, Troxel SA, Sandlow JI, Donovan JF:  Cost analysis of laparoscopic versus open varix ligation.  American Urological Association North Central Section Annual Meeting, Boca Raton, FL.  November 1994.

 

14.                 Sandlow JI, Cohen MB, Sandra A:  Expression of the c-kit ligand in a murine model of human subfertile conditions.  American Urological Association North Central Section Annual Meeting, Boca Raton, FL.  November 1994.

 

15.                 Sandlow JI, Kreder KJ.  Urologists’ practice patterns in response to reports of a possible link between vasectomy and prostate cancer.  American Society for Reproductive Medicine Annual Meeting, Seattle, WA.  October 1995.

 

16.                 Feng HL, Sandlow JI, Sandra A:  Expression and function of the c-kit proto-oncogene protein in mouse sperm.  Society for the Study of Reproduction Annual Meeting, Toronto, Ontario, Canada.  July 1996.

 

17.                 Sandlow JI, Donovan JF, Spark AET:  MESA/ICSI:  the importance of the embryologist.  American Urological Association North Central Section Annual Meeting, Tucson, AZ.  October 1996.

 

18.                 Sandlow JI, Feng HL, Sandra A:  Localization and function of the c-kit receptor in testis and sperm.  American Society for Reproductive Medicine Annual Meeting, Boston, MA.  November 1996.

 

19.                 Sandlow JI, Donovan JF, Sparks AET:  Evaluation of the male partner in couples undergoing assisted reproductive techniques.  American Society for Reproductive Medicine Annual Meeting, Boston, MA.  November 1996.

 

20.                 Sandlow JI, Feng HL, Sandra A:  Ultrastructural location of the c-kit receptor protein during mouse spermatogenesis.  Society for the Study of Reproduction Annual Meeting, Portland, OR.  August 1997.

 

21.                 Feng HL, Sandlow JI, Sandra A:  Presence of the c-kit receptor and its possible signaling transduction pathway in mouse sperm.  Society for the Study of Reproduction Annual Meeting, Portland, OR.  August 1997.

 

22.                 Feng HL, Sandlow JI, Sandra A:  Function of c-kit ligand (SCF) in the mouse sperm acrosome reaction and its possible signaling transduction pathway.  9th International Congress on Genes, Gene Families, and Isozymes.  San Antonio, TX; April 1997.

 

23.                 Feng HL, Sandlow JI, Sandra A:  The c-kit receptor and its function in human sperm.  23rd Annual Meeting, American Society of Andrology.  Long Beach, CA; March 1998.

 

24.           Schrepferman CG, Sandlow JI, Sparks AET:  Need for sperm cryopreservation at the time of vasectomy reversal.  American Urological Association North Central Section Annual Meeting, Chicago, IL.  September 1999.

 

 

Invited Lectures/Visiting Professorships

 

1.                    Laparoscopic Removal of a Renal Cyst.  AUAA Mississippi Valley Section Meeting, Cedar Rapids, IA.  March 1992.

 

2.                    The Use of PSA in Prostate Cancer Screening.  Family Practice Grand Rounds—Broadlawns Medical Center, Des Moines, IA.  August 1992.

 

3.                    PSA and Prostate Cancer.  General Surgery Grand Rounds—Veterans Administration Medical Center, Des Moines, IA.  October 1992.

 

4.                    Assisted Reproductive Techniques in Male Infertility.  Iowa Urological Society Annual Meeting, Iowa City, IA.  September 1995.

 

5.                    Management of the Infertile Male.  Iowa Lutheran Hospital, Des Moines, IA.  February 1996.

 

6.                    The Undescended Testicle.  Broadlawns Medical Center, Des Moines, IA.  May 1996.

 

7.                    Shattering the Myths About Male Infertility.  Society of Urologic Nurses and Associates-Mississippi Valley Section Meeting, Cedar Rapids, IA.  October 1996.

 

8.                    Expression of the c-kit Receptor and Stem Cell Factor in Testis and Sperm.  Department of Experimental Pathology Lab Group, Beth Israel Hospital, Boston, MA.  November 1996.

 

9.                    Evaluation of the Subfertile Male.  Perspectives in Urology.  Phoenix, AZ.  December 1996.

 

10.                 The Work-up and Treatment of Male Infertility.  Association of Operating Room Nurses, Iowa Chapter Meeting, Iowa City, IA.  March 1997.

 

11.                 Visiting Professor:  Male Infertility for the Family Physician.  Sioux City Family Practice Department, Sioux City, IA.  May 1997.

 

12.                 The State of the Art of Male Infertility. Iowa Urological Society Annual Meeting, Iowa City, IA.  September 1997.

 

13.                 Urologic Trauma.  General Surgery Grand Rounds, Iowa City, IA.  April 1998.

 

14.                 The Importance of the Male in the Work-up of the Infertile Couple.  Iowa Chapter of RESOLVE, Dubuque, IA.  May 1998.

 

15.                 Visiting Professor:  Cryptorchidism and Fertility.  5th Annual Andrology Conference, Charité Hospital.  Berlin, Germany. June 1998.

 

16.                 Visiting Professor:  MESA/TESE:  The U.S. Experience. 5th Annual Andrology Conference, Charité Hospital.  Berlin, Germany. June 1998.

 

17.                 The Role of the Urologist in Assisted Reproduction.  North Central Section of the American Urological Association Annual Meeting.  Amelia Island, FL.  November 1998.

 

18.                 Male Infertility for the Primary Care Physician.  Refresher Course for the Family Physician.  Iowa City, IA.  April 1999.

 

19.                 Male Infertility:  Diagnostic and Treatment Strategies.  Course Faculty.  94th Annual Meeting of the American Urological Association Dallas, TX. May 1999.

 

20.                 Visiting Professor: Shattering the Myths of Male Infertility. Medical College of Wisconsin.  Milwaukee, WI.  December 1999.

 

21.                 Advances in the Treatment of Benign Prostatic Hyperplasia.  Clarion Hotel and Conference Center.  Coralville, IA. March 2000.

 

22.                 Male Infertility.  Internet Chat on AmericasDoctor.com.  March 2000.

 

23.                 Male Infertility:  Diagnostic and Treatment Strategies.  Course Faculty.  95th Annual Meeting of the American Urological Association Atlanta, GA. May 2000.