CURRICULUM VITAE

 

 

 

 

NAME:                                                 Paul Jacob Turek, M.D.

 

 

PRESENT TITLE:                              Assistant Professor in Residence

                                                                Director, Male Reproductive Laboratory

                                                                Department of Urology

                                                                University of California San Francisco

                                                                San Francisco, California 94143-0738

 

 

 LINK TO:  http://Itsa.ucsf.edu/~uroweb/Uro/Index.html

 

TELEPHONE:                                    Office:   415-353-7352

 

EDUCATION:                                    Manchester High School

                                                                Connecticut

                                                                High School Diploma                                                                      1978

 

                                                                Yale College

                                                                New Haven, Connecticut

                                                                Degree:   Bachelor of Science (Biology)                                       1982

 

                                                                Stanford University School of Medicine

                                                                Stanford, California

                                                                Degree:   M.D.                                                                                     1987

 

 

POST-GRADUATE TRAINING:

 

                Surgical Intern                   Hospital of the University of Pennsylvania                              1987 - 1988

                                                                Philadelphia, Pennsylvania

 

                Surgical Resident              Hospital of the University of Pennsylvania                              1988 - 1989

                                                                Philadelphia, Pennsylvania

 

                Urology Resident              Hospital of the University of Pennsylvania                              1989 - 1993

                and Instructor                    Philadelphia, Pennsylvania

 

                Fellow and                          Department of Urology                                                                    1993 - 1994

                Instructor                             Baylor College of Medicine

                                                                Houston, Texas

 

 

ACADEMIC APPOINTMENTS

 

                Assistant Clinical             Department of Urology                                                    8/1994 - 1995

                Professor                              University of California

                                                                San Francisco, California

 

                Assistant Professor           Department of Urology                                                    1995 -

                in Residence                       University of California

                                                                San Francisco, California

 

                Clinical Assistant             Department of Urology                                                    1996-

                Professor                              Stanford University

 

 

HOSPITAL STAFF APPOINTMENTS:

 

                Moffitt Hospital-University of California                                                  Attending Staff Surgeon

                UCSF/Mt. Zion Medical Center                                                                                   Attending Staff Surgeon

                San Francisco General Hospital                                                                                   Attending Staff Surgeon

                Veterans Administration Medical Center                                                  Attending Staff Surgeon

                U.S. Naval Medical Center, Oakland                                                                          Consulting Staff

                Stanford University Hospital                                                                                        Visiting Staff Surgeon

 

 

BOARD CERTIFICATION AND LICENSURE

 

                American Board of Urology, Diplomate                                                                                     1996-

                American College of Surgeons, Fellow                                                                                       1997-    

                California State Dept. Health, High Complexity Laboratory Director                              1996-

                California State Dept. Health, Tissue Bank Director                                                              1996-

                California State Dept. Health, Fluoroscopy X-Ray Supervisor and Operator                1995-

                State of California, Medical License                                                                                            1993-                    

                U.S. Drug Enforcement Administration License                                                                     1989-

                State of Pennsylvania, Medical License                                                                                     1987-

               

 

ADMINISTRATIVE RESPONSIBILITIES

 

                Male Fertility Clinic, UCSF                                             Director                                                1994-

                Male Reproductive Laboratory-UCSF                         Director                                                1994-

                Sperm Donor Program and Cryobank-UCSF            Director                                                1994-

                Section of Urology, Veterans Administration           Assistant Chief                  1995-

                    Medical Center, San Francisco, CA

                Department of Urology, Web Site                 Director                                                1997-

                PROGENI  (Program in the Genetics                          Program Leader                 1998-

                    of Infertility)

                UCSF-Mt. Zion Urology Faculty Practice   Practice Manager                              1998-

                Northern California Resident Seminar                      Program Chairman                           1999-2000

                Faculty Search Committee, Depart. Ob-Gyn             Member                                                1999

                               

 

ACADEMIC HONORS AND AWARDS:

 

                Yale Club of Hartford Achievement Grant                                                                                                1980

                Phi Beta Kappa, Yale College                                                                                                                        1981

                Summa cum laude, Yale College                                                                                                  1982

                Henry J. Belknap Prize in Biology (Senior thesis)                                                                   1982

                Research Honors, Stanford graduation                                                                                                     1987

                First Prize, Resident Essay Competition, Philadelphia Urological Society                     1991

                First Prize, Resident Essay Competition, Philadelphia Urological Society                     1992

                Henry Weyrauch Award, 43rd Western Urologic Forum                                                                     1994

                Best Poster, Male Infertility Session, American Urological Association                                          1995

                James L. Goebel Grand Prize, Posters, West. Section, American Urological Assoc.     1995

                Best Poster, Etiology of Male Infertility, American Urological Association                    1996

                Second Prize, Posters, Western Section, American Urological Association                    1996

                UCSF Young Faculty Development Award                                                                                              1996

                Best Poster Prize, Etiology of Male Infertility, American Urological Association         1997

                Second Prize, Clinical Research, Northern California Urological Society                      1997

                Best of Session, Poster, Western Section, American Urological Association                  1997

                Citation of Distiguished Contribution, RESOLVE                                                                  1997

                AUA/EUA Academic Fellowship European Exchange                                                                       1998

                Society of Male Reproduction and Urology Travelling Award                                                          1998

                Outstanding Leadership, Clinical Preceptor, UCSF Class of 2000, Teaching Award 1998

                First Prize, Posters, Western Section, American Urological Association                                         1998

                Life member, National Registry of Who’s Who, Year 2000                                                  1999

                Young Surgeon Award, American College of Surgeons, N. Cal. Chapter                                       2000

 

 

PROFESSIONAL ACTIVITY

 

SOCIETY MEMBERSHIP

 

                American College of Surgeons

                American Urological Association

                Societe Internationale d'Urologie

                American Society for Reproductive Medicine

                American Association of Clinical Urologists

                Society for the Study of Male Reproduction

                American Society of Andrology

                Society for Male Reproduction and Urology

                Pacific Coast Fertility Society

                RESOLVE

                Northern California Urologic Society

                Western Section, American Urological Association

                Northern California Chapter, American College of Surgeons

                Honorary Member, Al-Alzhar University Center for Research and Management of Impotence                                                              and Infertility, Cairo, Egypt

                Association for Voluntary Surgical Contraception (AVSC International).

                Stanford Alumni Association

                Yale Alumni Association

 

EDITORIAL BOARD MEMBERSHIP

 

                Current Opinions in Urology (Andrology)                                                                               1994 -

 

AD HOC EDITORIAL ACTIVITY

 

                Journal of Urology                                                                                                                            1995 -

                Medical Practice and Principles                                                                                   1996-

                Journal of Clinical Endocrinology and Metabolism                                                               1996-

                Journal of Andrology                                                                                                                       1996-

                The Western Journal of Medicine                                                                                 1997-

                Fertility and Sterility                                                                                                                        1998-

                European Journal of Urology                                                                                                        1998-

                American Journal of Medicine, Ethics and Law                                                                      1999-

                Human Reproduction                                                                                                                     1999-

                Biology of Reproduction                                                                                                 1999-

 

 

SERVICE TO NATIONAL ORGANIZATIONS

 

                American Society for Reproductive Medicine

                                Abstract Committee                                                                                                          1996-1998

                                Urology Representative, National Advisory Council ASRM                              1997-

                                Co-Director, ASRM-NRAC Regional Post-Graduate Course                               1998-1999

                                Patient Education Committee                                                                                        1999-

 

                Society for the Study of Male Reproduction

                                Member-at-Large                                                                                                               1997-1998

                                Chairman, Audit Committee,                                                                                        1997-1998

                                Nominating  Committee                                                                                  1998-1999

 

                American College of Surgeons

                                Co-Chairman, Urology Section, Northern California Chapter                            1998-

 

                American Society of Andrology

                                Membership committee                                                                                                   1996-

 

                Society for Male Reproduction and Urology

                                Board of Directors Nominee                                                                                          1996

                                Nominating Committee                                                                                   1997

                                Chairman, Membership Committee                                                                            1999-

 

                RESOLVE

                                Medical Advisory Board, N. Cal. Chapter                                                 1995-

 

                Association for Voluntary Surgical Contraception (AVSC International).      1996-

                                Advisory Board Member                                                                                

 

                World Health Organization Fellowship Supervisor                                                              1996-

 

                WaterWerks. Non-profit corporation for urology                                                   1993-

                                President

 

                Yale Alumni Association                                                                                                               1993-

                                Admissions Committee Interviewer

 

                Mentor Corporation

                                National Medical Director, FDA-Testis Prosthesis Trial                      1995-

 

                Sperm Bank of California

                                Medical Advisory Board                                                                                 1999-                                                    

 

UNIVERSITY AND PUBLIC SERVICE

 

                Veterans Administration Medical Center, San Francisco                                                    

                                Surgical Staff Committee                                                                                 1994-

                                Infection Control Committee                                                                                          1994

                                Antibiotic Usage Committee                                                                                          1996-

                                Co-Chairman, Committee of ICU and TCU utilization                                          1996

                                VISN Inpatient Redesign Team                                                                                    1996

                                Surgical Informed Consent Committee                                                                       1998

                                Quality Assurance Committee, Surgical Service                                                     1999-

 

                University of California, San Francisco

                                Admissions Committee                                                                                       1995-present

 

                NICHD Program Project. Advisory Board,   "Individual, Family and                              1997-    

                                Societal Outcomes of Infertility" UCSF Dpt. of Family and

                                Community Medicine  (P.I. M. Croughan-Minihane Ph.D)

               

                Program Leader, UCSF-Stanford Healthcare PROGENI (Program in the        1998-

                                Genetics of Infertility)

                               

                Chairman, Urology Resident Selection Committee                                                 1999-

 

                Director, Department of Urology Annual Postgraduate Course                                         1997

 

                Director, Department of Urology, Annual Alumni Reception                                             1997-

 

                Mentor, Volunteer Services, UCSF                                                                                               1996-

               

                Proctor, Urology in-Service Examination                                                                  1994-1996

 

 

VISITING PROFESSORSHIPS

 

Treatment of Male Factor Infertility: From Insemination to ICSI. Guest of the VI Congress F.L.A.S.E.F., Panama City, Panama, March 22-26, 1999.

 

ICSI and Male Genetic Infertility: Hope and Hard Facts. Department of Urology, New York University School of Medicine. New York, NY, August 18-20, 1999.

 

Fertility in Spinal Cord Injury Patients. IX Congress of IMSOP. University of Florence, Department of Urology, Florence, Italy. October 26-30, 1999.

 

 

INVITED LECTURES, SCIENTIFIC AND PROFESSIONAL MEETINGS

 

Invited Speaker.  Renal Physiology for Surgeons.  Grand Rounds Lecture, The Department of Surgery, Pennsylvania Hospital, Philadelphia, PA.  July 1992.

 

Invited Speaker. Immunology in Urology. Research Conference, Scott Department of Urology, Baylor University, Houston, TX , November 1991.

 

Invited Speaker. The Prostate. Grand Rounds Lecture, The Department of Medicine, Hospital of the University of Pennsylvania, Philadelphia, PA.  March and May 1993.

 

Invited Speaker. Immunologic Infertility.  Grand Rounds Lecture.  The Department of Urology, Baylor College of Medicine, Houston, TX, January 1994.

 

Invited Speaker. New Developments in the Diagnosis and Treatment of Male Infertility. Grand Rounds, The Department of Urology, November 5, 1994.

 

Invited Speaker. How Does Cancer Treatment Influence Sperm Quality?  UCSF Pediatric Oncology Seminar, March 20 1995.

 

Invited Speaker.  Evaluation of the Infertile Male.  Northern California RESOLVE Annual Symposium.  Mills College, Oakland, CA.  June 6, 1995.

 

Invited Speaker.  New Concepts in Ejaculatory Duct Obstruction.  Grand Rounds. UCSF, Department of Urology.  September 9, 1995.

 

Invited Speaker. Infertility: A Male Perspective.  Northern California RESOLVE conference.  September 13, 1995.

 

Invited Speaker.  Environmental Factors and Male Infertility.  Northern California RESOLVE Focus Seminar. Alta Bates Hospital, Berkeley, CA.  October 16, 1995.

 

Invited Speaker.  A Dynamic Duo: The Andrology Laboratory and the Clinical Management of Infertility. Grand Rounds, UCSF Department of Laboratory Medicine, December 19, 1995.

 

Invited Speaker. The Evaluation of the Infertile Male. Ambulatory Medicine Rounds, UCSF, February 5, 1996 .

 

Invited Speaker. Surgery for Male Infertility. Ambulatory Surgical Center Staff Rounds, April 4, 1996.

 

Invited Keynote Speaker. New Developments in the Treatment of Male Infertility. Turkish Urologic Society, May 20, 1996,  Istanbul, Turkey.

 

Invited Speaker. Evaluating the Infertile Male and Ultimate IVF: ICSI, Sperm Extraction. RESOLVE of Northern California Annual Symposium (Creative Family Building), Mills College, Oakland CA, June 1 1996.

 

Invited Keynote Speaker. Male Infertility: A Prescription for Survival. Chairman: Frank Hinman Jr.  Society of University Urologists, American College of Surgeons Annual Meeting, San Francisco, CA Oct 10, 1996.

 

Invited Keynote Speaker.  The Use of Systematic Fine Needle Aspiration "Mapping" of the Testis to Detect Sperm in Azoospermic Men, and Varicocele Repair: Techniques, Cost and Outcome. Congress of Public Hospitals, Istanbul, Turkey, Dec 3-6, 1996.

 

Invited Speaker.  How to Pick a Sperm for a Test-Tube Baby. Grand Rounds Lecture, Department of Urology, UCSF.  December 11, 1996.

 

Invited Keynote Speaker. Back to the Future: Innovations in the Treatment of Male Infertility. Plenary Session, AUA annual meeting. Course directors A. Belker and R. Meacham, New Orleans, LA. April 14, 1997.

 

Invited Speaker.  Preserving and Restoring Fertility in Young Men. Pediatric Oncology Seminar Series. Department of Oncology, UCSF. May 9 1997.

 

Invited Speaker.  Infertility and Kallman's Syndrome. Department of Medicine, Division of Endocrinology, UCSF, Patient Care Conference. May 13, 1997.

 

Invited Speaker.  Male Germ Cell Transplantation. Department of OB-Gyn Research Seminar, UCSF, May 23, 1997.

 

Invited Speaker.  How to Treat Obstruction in the Male and Male Factor: ICSI with the Embryologists. RESOLVE Annual Symposium, Nothern California Chapter, Oakland, CA, June 7 1997

 

Invited Speaker.  Male Factor Infertility-What's New. RESOLVE Seminar, Alta Bates Hospital, Berkeley, CA, August 19, 1997.

 

Invited Keynote Speaker. What Everyone Should Know About Male Infertility. Society of Urologic Nurses Symposium, Veterans Affairs Medical Center, San Francisco, CA November 1, 1997.

 

Invited Speaker.  How to Get Sperm From A Rock. Grand Rounds Guest Lecture, Department of Urology, UCSF. November 12, 1997.

 

Invited Keynote Speaker.  Preserving and Restoring Fertility in Young Men. Grand Rounds Lecture. Social Securitie Hospital, Panama City, Republic of Panama, January 14, 1998.

 

Invited Keynote Speaker. Sperm From a Rock: Fine Needle Aspiration Mapping in Male Infertility. European Association of Urology Meeting, Barcelona, Spain March 21, 1998

 

Invited Keynote Speaker. Rat Seminal Vesicle Urodynamics: The Seminal Vesicle as Bladder of the Reproductive Tract. EAU Exchange Program, Department of Urology, University of Berne, Berne Switzerland, March 28, 1998.

 

Invited Speaker.  Sperm From a Rock: Fine Needle Aspiration Mapping in Male Infertility. Center for Reproductive Medicine, Free University of Brussels, Brussels, Belgium, April 2, 1998.

 

Invited Keynote Speaker. The New Genetics of Male Infertility. EAU Exchange Program, Department of Urology, University of Warsaw, Warsaw, Poland, April 5, 1998.

 

Invited Speaker.  Cytokines and Male Autoimmune Infertility. Grand Rounds, Department of Endocrinology, UCSF, San Francisco, April 22, 1998.

 

Invited Speaker.  Male Infertility Treatment: The Edge of Technology. Brown Bag Lunch Series. Veterans Affairs Medical Center, San Francisco, CA. May 7, 1998.

 

Invited Speaker.  Male Workup and Initial Treatment and Reasons to Consider ICSI. Reaching for Resolution, RESOLVE Symposium, Mills College, Oakland, CA. June 6, 1998.

 

Invited Speaker.  General Outpatient Urology. Lecture, Primary Care Residency Training Program, UCSF, San Francisco, CA. May 5, 1998.

 

Invited Keynote Speaker.. New Techniques that Turn "Sterility" Into Fatherhood, and The New Genetics of Male Infertility. Invited Speaker, Arizona Urological Society Annual Meeting, Prescott, AZ July 17-19, 1998.

 

Invited Speaker.  Simple and High Technology Treatments for Male Infertility. Grand Rounds Lecture, Department of Ob-Gyn, University Hospital, Fresno, CA. July 30, 1998.

 

Invited Speaker.  Everything That You Need to Know About Male Infertility. Brown Bag Lecture Series. UCSF. August 19, 1998.

 

Invited Speaker.  The Brand New Genetics of Male Infertility. Grand Rounds Lecture, Department of Urology, UCSF, San Francisco, CA September 9, 1998.

 

Invited Keynote Speaker SMRU Travelling Award Lecture: Sperm Procurement Techniques. San Francisco, CA October 4, 1998.

 

Invited Speaker.  ASRM Roundtable Lecture: Helping the Couple with Non-obstructive Azoospermia to Conceive. San Francisco, CA. October 7 1998.

 

Invited Keynote Speaker.. Biking, Baking and Boxers: A Practical Guide to Male Infertility. Kaiser Permanente Medical Group-New Concepts in Reproductive Gynecology and Fertility. October 10, 1998. 

 

Invited Speaker,  Male Fertility and Radiation Therapy. Chief Resident Seminar Series, UCSF Department of Radiation Therapy, December 6, 1998.

 

Invited Keynote Speaker.. UCSF Dean's Seminar Series. Spermatogenesis and Sporulation: Fertility and Infertility in Man and Yeast. Lecture with Renee Reijo PhD and Ira Hirschkowitz PhD, February 22, 1999.

 

Invited Speaker,  VA Medical Center Annual Nurses Symposium, Male Fertility: The Cutting Edge. San Francisco, CA. March 18, 1999.

 

Keynote Speaker, UCSF-Mt Zion Brown Bag Lecture Series. Viagra: An Update. Herbst Hall, Mt. Zion Hospital, San Francisco, April 2, 1999.

 

Invited Speaker, Stanford University Health Library Symposium. Demystifying Infertility. Stanford, CA. May 13, 1999.

 

Invited Speaker.  Male Infertility Workup and Genetic Causes of Male Infertility. Creative Family Building, Annual RESOLVE Symposium, Mills College, Oakland, CA. June 5, 1999.

 

 

INVITED LECTURES/INTERVIEWS, NON-SCIENTIFIC AND MEDIA

 

KQED radio Forum, Topic: Infertility.  Broadcast live in San Francisco.  February 21, 1995.

 

ABC World News Tonight, American Agenda.  Infertility. March 1995.

 

CBS Televison, Day & Date, Are Sperm Counts Dropping? Broadcast January 10, 1996.

 

Nightly News, Channel 5, CBS. Are Sperm Counts Dropping? Broadcast February 28, 1996.

 

ABC Good Morning America; The Hypo-osmotic swelling test. Joan London interview. June 26, 1997

 

ABC News.Com. "Chat Room" on the Internet; The Hypo-osmotic Swelling Test. June 26, 1997

 

CNN News, National broadcast. The Hypo-osmotic Swelling Test for Viable Sperm. June 27-29, 1997

 

The Sunday London Times Newspaper, Interview: Hypo-osmotic Swelling Test, July 6, 1997

 

BBC, London England, Interview for broadcast. Sperm Hypo-osmotic Swelling Test, July 10, 1997

 

Interview, The Journal Inquirer, Manchester, CT on The Sperm Swelling Test, July 18 1997

 

Interview, The Sacramento Bee Newspaper, The Use of Sperm from the Dead, July 19 1997

 

Interview, The Hartford Courant Newspaper, Hartford, CT on The Sperm Swelling Test, July 20 1997

 

Interview, KCBS News, New York, The Sperm Swelling Test, August 20, 1997

 

CBS "This Morning" News Show. The Diagnosis and Treatment of Male Infertility, December 1, 1997

 

Commentary on Declining Sperm Counts. ABC News, Channel 7, San Francisco. August 24, 1998.

 

National Public  Radio (KALW  in SF). Prevention, Diagnosis and Treatment of Male Infertility. February 18th and 25th, 1999. San Francisco

 

ABC 20/20 News. Interview on Posthumous Reproduction. April 5, 1999.

 

Interview, People Magazine, Posthumous Reproduction, April 19, 1999.

 

Interview, National Public Radio Progam "Beyond Computers." The Ethics of Posthumous Reproduction. April 17, 1999

 

Interview, PBS Television, Frontline. The Ethical and Genetic Aspects of Infertility. June 1, 1999.

 

Interview, San Francisco Business Weekly, PROGENI and the Genetics of Infertility. August 3, 1999

 

Interview, The Oakland Tribune, PROGENI Program and the Genetics of Infertility, September 19, 1999

 

Interview, Life Magazine 1999 Year Book, Post-Mortem Sperm Retrieval, October 14, 1999

 

Interview, People Magazine, Post-Mortem Sperm Retrieval, November 10, 1999

 

Interview, CBS/KPIX TV, Channel 5. The Story of Testis Prostheses. November 26, 1999.

 

Interview, New York Times, Commentary on TransgenICSI (Gerald Schatten PhD). December 27, 1999.

 

Interview, California Health Care Foundation, Healthline, TransgenICSI. December 23, 1999

 

Interview, MyPrimetime.com. Germ Cell Transplantation. January 6, 2000

 

 

TEACHING

 

Medical  Student and Resident Teaching

 

Lecturer, Surgery 110. Surgical Subspecialties. Impotence/Infertility                  1.0 hrs/mo.       1994 present

Lecturer, Medicine 112 . Ethics in Medicine                                                                 3.0 hrs/yr.         1995-1997

Lecturer, Physiology 101                                                                                                    3.0 hrs/yr          1999-present

Instructor, Urology Residents.                                                                                          100 hrs/mo.      1994-present Instructor, Reproductive Endocrinology Fellows                                                                                                       8.0 hrs/mo.       1995-1998

Lecturer, Core Lecture Series, Department of Ob-Gyn                                               1.5 hrs/mo.       1996-present

Lecturer, Core lecture Series, Internal Medicine Department                                  1.0 hrs/mo.       1996-present

                                                                                                                                               

University Courses

 

Course Director,  Resident Seminar Series in Infertility, UCSF Department of Urology. 1994-present.

 

Invited Lecturer.  Evaluation of the Infertile Male and Sperm Aspiration Techniques.  UCSF Department of Urology Annual Postgraduate Course: Technological Innovations in Urology, Fairmont Hotel, San Francisco, Nov 10-11, 1994.

 

Invited Lecturer.  Adolescent Varicoceles: When to Treat?  UCSF Pediatric Urology Course, October 14-15 1994.

 

Invited Lecturer.  Complications of Testis Cancer Therapy: Secondary Malignancies and Infertility. UCSF Department of Urology Annual Postgraduate Course: Innovations in Urology, Fairmont Hotel, San Francisco, CA.  October 6-7, 1995.

 

Invited Lecturer.  What Every Gynecologist Needs to Know About Male-Factor Infertility. Symposium, Clinical Infertility and Reproductive Endocrinology, UCSF Department of OB-GYN, April 25-26 1996.

 

Invited Lecturer.  Male Factor Infertility: What You Need to Know. Symposium, Clinical Ob/Gyn and Gynecologic Histopathology and Primary Care for the Practicing Gynecologist. Department of Ob-Gyn, UCSF, ANA Hotel, San Francisco, October 21-24, 1996.

 

Invited Lecturer. Varicocele Repair: Techniques, Cost and Outcome and Cost Effective Evaluation of Male Infertility. UCSF Department of Urology Annaul Postgraduate Course: Technical Innovations in Urology, Sheraton Palace Hotel, San Francisco, CA  November 7-8, 1996.

 

Co-Chair and Lecturer.  Cost Effective Evaluation of the Infertile Male, and Treatable Conditions in Male Infertility, and Genetic Causes of Male Infertility. UCSF Annual Post-Graduate Course: Strategies in Office Based Urology.  Ritz Carlton Hotel, San Francisco, CA. Dec 12-13, 1997.

 

Invited Lecturer.  Management of Male Infertility. Advances in Endocrinology and Metabolism Course, Divisions of Endocrinology and Metabolism, Department of Medicine, UCSF. Miyaki Hotel,  San Francisco, March 6-7 1998.

 

Invited Lecturer.  Male Fertility Diagnosis and Treatment: What's New for 1998? UCSF Annual Update in Clinical OB-Gyn Course. Hyatt Hotel, San Francisco, CA. October 10, 1998.

 

Invited Lecturer.  Fertility Issues in Patients with Congenital Anomalies. Innovations in Urology Post-Graduate Course, UCSF Department of Urology. Ritz Carlton Hotel, San Francisco, CA. December11-12, 1998.

 

Invited lecturer, ICSI, Genetics and Male Infertility. Grand Rounds, Department of Ob-Gyn, Summit Medical Center, Oakland Ca, July 13, 1999.

 

Invited lecturer, Intracytoplasmic Sperm Injection: Outcomes and risks. UCSF Annual OB-Gyn Update: What Does The Evidence Tell Us? San Francisco, CA, November 6, 1999.

 

 

National Courses

 

Invited Lecturer.  American Urological Association Post Graduate Course. The Pituitary-Gonadal Axis in the Infertile Male: How to Manage an Endocrine Workup.  Advances in Male Infertility, Chairman LI Lipshultz MD. Las Vegas, NV.  April 26, 1995.

 

Invited Lecturer.  American Urological Association Post-Graduate Course. Diagnostic Strategies in Male Infertility Treatment: Astheno-teratozospermia.  Chairman Harris Nagler  MD.  Orlando, FL.  May 8, 1996.

 

Invited Lecturer. AUA Office of Education Postgraduate Course. Introduction to Clinical Microsurgery. Chairman LI Lipshultz MD. Houston, Texas, June 21-23, 1996.

 

Co-Director and Lecturer. AUA Office of Education Postgraduate Course. Innovations in Male Infertility. Cancun, Mexico, February 23-26, 1997.

 

Invited Lecturer. American Urological Association Postgraduate Course. How to Manage the Pituitary Gonadal Axis in the Evaluation of the Infertile Male, and Empiric Medical Therapy for Infertility. Chairman, Larry Lipshultz MD, New Orleans, LA. April 12, 1997.

 

Invited Lecturer.  AUA, Confederacion Americana de Urologia and Urologic Society of Panama: Seminar on Erectile Dysfunction, Peyronie's Disease, Priapism and Male Infertility. Panama City, Republic of Panama, January 13-16, 1998.

 

Invited Lecturer. American Urological Association Postgraduate Course. How to Manage the Pituitary Gonadal Axis in the Evaluation of the Infertile Male, and Empiric Medical Therapy for Infertility. Chairman, Larry Lipshultz MD, San Diego, CA. May 11, 1998.

 

Invited Lecturer.  ASRM Postgraduate Course "Male Reproduction: Basic, Genetic, and Clinical Information for the Next Millenium." Lectures included: Spermatogenesis: Cell types, Mitosis, Meiosis, Spermiogenesis; Genomic DNA Micromorphology; Ejaculatory Duct Obstruction Diagnosis and Treatment; Syndromes with Reproductive Dysfunction; Utility of FNA Mapping for Sperm Retrieval.  ASRM Annual Meeting, San Francisco, CA October 3-4, 1998.

 

Invited Lecturer. American Urological Association Postgraduate Course. How to Manage the Pituitary Gonadal Axis, Empiric Medical Therapy for Infertility and the New Genetics of Male Infertility Chairman, Larry Lipshultz MD, Dallas, TX. May 1, 1999.

 

Co-Chairman, American College of Surgeons, Northern California Chapter. Emerging Technologies in the Treatment of BPH: Microwaves, Lasers and Ultrasound. May 7, 1999, San Francisco, CA.

 

Chairman, American College of Surgeons, Northern California Chapter. Gene Therapy in Urology. May 3, 2000, San Francisco, CA.

 

 

International Courses

 

Invited Lecturer. Treatment of Male Factor Infertility: From Insemination to ICSI and Cost-Effective Evaluation of Male Infertility. Guest of the VI Congress F.L.A.S.E.F., Panama City, Panama, March 22-26, 1999.

 

Invited Lecturer. IX Congress of So. M.I. Par. Sexuality and Fertility Among Spinal Cord Injury Patients. Florence, Italy. October 27-30, 1999.

 

 

STUDENTS AND POSTDOCTORAL FELLOWS SUPERVISED                          

 

1994-1995            Abdel K. Younes M.D.  Al-Alzhar University Center for Research and Management of                                                            Impotence and Infertility, Cairo, Egypt

 

1996                       Satya Prakash M.D. Reader, WHO Visiting Post Doctoral Fellowship, Department of                                                              Urology, Post-Graduate Institute of Medical Sciences, Haryana, India.

 

1995-97                 Khalid Aslam BS. Premedical Student Research (20 hrs/wk)

 

1997                       Pajvi Mehta PhD, Science Director, Hope Infertility Clinic, Bangalore, India

 

1997                       Nathan Bachtell BS. UCSF Student Research Committee Summer Fellowship 1997

 

1997-98                 Neelima Vegasna BS. Premedical Student Research (4 hrs/wk)

 

1998                       Manmohan Misro M.D. Research Officer, WHO Visting Post-Doctoral Fellowship,                                                   Department of Reproductive Medicine, National Institute of Health and Family Welfare,                                    New Delhi, India.

 

1998-99                 David Nudell MD. Gianinni Postdoctoral Fellow. Laboratory of Renee Reijo Ph.D UCSF.

 

1998-99                 Douglas Lee. Premedical Student Research. (4 hrs/wk)

 

1998-                     Michael Singer B.S. UCSF Medical Student Research (4 hrs/wk)

 

1999                       Mariano Cohen M.D. Universitas Clinicas, Department of Urology, University of Buenos Aires

 

2000                       Selahittin Kayan M.D. Asistant Professor, Dept of Urology; University of Istanbul, Istanbul Turkey

 

 

PUBLICATIONS

 

PEER REVIEWED/ORIGINAL MANUSCRIPTS

 

1. Kerkering TM, Schwartz PM, Espinal-Ingroff A, Turek PJ, Diasio RB.  5-Fluorocytosine Susceptibility of Pathogenic Fungi in the Presence of Allopurinol: Potential of Improving theTherapeutic Index  of 5-Fluorocytosine.  Antimicrobial Agents and Chemotherapy, 24 (3): 448-449, 1983.

 

2. Schwartz PM, Turek PJ, Hyde CM, Cadman EC, Handschumacher RE.  Altered Plasma Kinetics of 5-FU at High Dosage in Rat and Man.  Cancer Treatment Reports, 69 (1): 133-136, 1985.

 

3. Bashford CL, Alder GM, Gray MA, Micklem KJ, Taylor CC, Turek PJ, and Pasternak CA.  Oxonol Dyes as Monitors of Membrane Potential: The Effect of Viruses and Toxins on the Plasma Membrane Potential of Animal Cells in Monolayer Culture and in Suspension.  Journal of Cellular Physiology, 123 (3): 326-336, 1985.

 

4. Schwartz PM, Moir RD, Hyde CM, Turek PJ, Handschumacher RE.  Role of Uridine Phosphorylase in the Anabolism of 5-Fluorouracil.  Biochemical Pharmacology, 34 (19): 3385-3389, 1985.

 

5. Turek PJ, Grumet FC, Engelman EG. Molecular Variants of the HLA-B27 Antigen in Healthy Individuals and Patients with Spondyl-arthropathies.  Immunological Reviews, 86: 71-91, 1985.

 

6. Alpert SD, Turek PJ, Foung SK, Engelman EG.  Human Monoclonal Anti-T cell Antibody from a Patient with Juvenile Rheumatoid Arthritis.  Journal of Immunology, 138 (1): 104-108, 1987.

 

7. Turek PJ, Malloy TR, Cendron M, Carpiniello V, Wein AJ.  KTP-532 Laser Ablation of Urethral Strictures.  Urology, 40 (3): 330-334, 1992.

 

8. Rovner E, Turek PJ, Duckett JW.  Ureterostomy in-situ.  Rediscovering an Old Technique.  Society for Pediatrics Newsletter, 1993.

 

9. Turek PJ, Ewalt DH, Snyder HM and Duckett JW.  Normal Epididymal Anatomy in Boys.  Journal of Urology, 151 (3): 726-727, 1994.

 

10. Turek PJ, Ewalt DH, Snyder HM, Stampfers D, Blyth B, Huff DS and Duckett JW.  The Absent Cryptorchid Testis: Surgical Findings and Their Implications for Diagnosis and Etiology.  Journal of Urology, 151 (3): 718-721, 1994.

 

11. Barba CA, Kauder D, Schwab, CW, Turek PJ.  Pelvic Kidney Laceration: An Unusual Complication of Percutaneous Diagnostic Peritoneal Lavage-Case Report.  Journal of Trauma, 36: 277-279, 1994.

 

12. Turek PJ, Gilbaugh J.H, Lipshultz LI.  Imaging in the Diagnosis and Treatment of Male Infertility. Current Opinion in Urology, 4: 156-161, 1994.

 

13. Mozley PD, Heyman S,  Duckett JW, Turek PJ,  Snyder HM, Maislin G, Beshaim H. Direct Vesicoureteral scintography: Quantifying the Early Outcome Predictors in Children with Primary Reflux.  Journal of Nuclear Medicine, 35: 10, 1994

 

14. Turek PJ, Williams RW, Gilbaugh JH, Lipshultz LI.  The Reversibility of Anabolic-Induced Azoospermia.  Journal of Urology, 153 (5): 1628-1630, 1995.

 

15. Turek PJ.  Declining semen quality in adults.  Editorial Commentary.  Current Opinions in Urology, 5(4):1995.

 

16. Turek PJ, Kim M, Gilbaugh JH, Lipshultz LI.  The Clinical Characteristics of 82 Patients with Sertoli-Cell Only Syndrome. Fertility & Sterility, 64: 1197, 1995

 

17. Turek PJ, Tomaczecki JE, Malkowicz SB, Wein AJ, Peehl D.  The Role of the Sertoli Cell in Active Immunosuppression in the Human Testis.  British Journal of Urology, 77: 891-895, 1996.

 

18. Turek PJ, Magana JO, Lipshultz LI.  Semen Parameters Before and After Transurethral Surgery for Ejaculatory Duct Obstruction. Journal of Urology, 155: 1291-3, 1996.

 

19. Nguyen HT, Etzell J, Turek PJ.  Normal Human Ejaculatory Duct Anatomy: A Study of Cadaveric and Surgical Specimens.  Journal of Urology, 155: 1639-1642, 1996

 

20. Turek P.J.  Male Infertility Redefined: Back to the Basics. Journal of Urology,  155: 1643, 1996

 

21. Chang JJ and Turek PJ. ART and the Treatment of Male Infertility: The Good and the Bad. Current Opinion in Urology. 6: U193, 1996.

 

22. Kim ED, Gilbaugh JH, Patel VR, Turek PJ and Lipshultz LI. Testis Biopsies Frequently Demonstrate Sperm in Azoospermic Men with Significantly Elevated FSH Levels. Journal of Urology, 157: 144, 146, 1997.

 

23. Smikle CB and Turek PJ.  Hypoosmotic Swelling Can Accurately Determine the Viability of Nonmotile Sperm.  Molecular Reproduction and Development. 47: 200-203, 1997.

 

24. Turek PJ and Smikle CB. Viability of Non-Motile Sperm. Assisted Reproduction Reviews. 7: 34-38, 1997.

 

25. Turek PJ, Imok Cha, and Ljung, B-M. Systematic Fine Needle Aspiration of the Testis: Correlation to Biopsy and the Results of Organ “Mapping” for Mature Sperm in Azoospermic Men. Urology. 49: 743-748, 1997.

 

26. Nudell D. and Turek PJ.  Is Fertility Impaired After Unilateral Cryptorchidism? Curr Opin Urol. 7:3, 1997.

 

27. Freedland SJ, Cha I, Turek PJ. Non-Palpable Leydig Cell Tumors Diagnosed by Fine Needle Aspiration. Journal of Urology, 158: 543-544, 1997.

 

28. Turek PJ, Aslam KH, Younes A.K, Nguyen HT. Observations on Seminal Vesicle Dynamics in an InVivo Rat Model. Journal of Urology. 159: 1731-1734, 1998.

 

29. Nudell DM, Conaghan J, Pedersen RA, Givens CR, Schriock ED and Turek PJ. The Mini-MESA for Sperm Retrieval: A Study of Urological Outcomes. Human Reproduction. 13: 1260-1265, 1998.

 

30. Turek P.J. Boxers and Biopsies: Separating Fashion From Fact in Male Infertility. Journal of Urology. 160: 1337, 1998

 

31. Kostiner DR, Turek PJ and Reijo RA. Male Infertility: Analysis of the Markers and Genes on the Human Y Chromosome. Human Reproduction. 13: 3032-3038, 1998.

 

32. Turek PJ, Nudell DM and Conaghan J. Methods of Epididymal Sperm Retrieval: A Urologic Perspective. Assisted Reproduction Reviews. 9: 60-64, 1999.

 

33. Turek PJ, Givens C, Schriock ED, Meng M, Pederson RA and Conaghan J. Testis sperm extraction and intracytoplasmic sperm injection guided by prior fine needle aspiration mapping in nonobstructive azoospermia. Fertility and Sterility. 71: 552-8, 1999

 

34. Bachtell N, and Conaghan J. and Turek PJ. The Relative Viability of Human Spermatozoa from the Testis, Epididymis and Vas Deferens Before and After Cryopreservation. Human Reproduction. 14: 101-104, 1999.

 

35. Black LD, Nudell DM, Cha I, Cherry AM and PJ Turek. Compound Genetic Defects as a Cause of Male Infertility. Human Reproduction. In press.

 

 

ORIGINAL MANUSCRIPTS SUBMITTED

 

Turek P.J, I. Cha, Ljung, B-M., and Conaghan J. Diagnostic Findings From Testis Fine Needle Aspiration Mapping in Obstructed and Non-Obstructed Azoospermic Men.

 

Meng MV, Ljung  B-M and Turek PJ. The Relationship Between Classic Histologic Pattern and Sperm Findings on Fine Needle Aspiration Map in Infertile Men.

 

Nudell DM, Castillo M, Turek PJ, Carleton V, and Reijo Pera, R. Defective DNA repair in infertile men.

 

Castillo M, Nudell DM, Turek PJ, and Reijo Pera R. Expression of DNA repair genes in infertile men.

 

Cohen M, Schriock E, Conaghan J, and Turek PJ. Pregnancy and birth with ICSI for infertility due to Kartagener syndrome.

 

Golden B, Lee D, Givens C, Schriock E, Ryan I, Conaghan J, and Turek PJ. IVF/ICSI with epididymal sperm: comparative fertilization rates with fresh and cryopreserved sperm from the same couples.

 

 

TEXT ILLUSTRATIONS

 

Zderic, SA and Hanno PM. Cutaneous vesicostomy and suprapubic urinary diversion. In: Mastery of Surgery: Urology. J.E. Fowler, Editor. Little, Brown and Co., Boston. 1992.

 

 

CHAPTERS/POPULAR JOURNALS

 

1. Turek PJ, Malloy TR.  Prosthetics.  In: High Tech Urology.  Edited by J.A.Smith Jr.  W.B Saunders and Co, 1992.

 

2. Turek PJ, Savage E.  Kidney and Urinary Tract Physiology.  In:  Essentials of Basic Science in Surgery. Edited by S. Fishman, E. Savage and L. Miller.  Lippincott Co., 1993.

 

3. Turek PJ and VanArsdalen K.N. Male Fertility and Infertility.  In:  A Clinical Manual of Urology.  Edited by P. Hanno and A.J. Wein.  Apple-Century-Crofts, 1994.

 

4. Turek PJ and Lipshultz LI.  Immunologic Infertility.  In: Urology Clinics of North America.  Edited by         L.I. Lipshultz. W.B.Saunders & Co, volume 21 (3): August 1994.

 

5. Turek PJ and Lipshultz LI.  Varicocele Controversies. I Pathology and Pathophysiology.  In: AUA Update Series. 14: Lesson 14, 1995.

 

6. Turek PJ and Lipshultx LI.  Varicocele Controversies. II.  Diagnosis and Management.  In: AUA Update     Series. 14: Lesson 13, 1995.

 

7. Turek PJ and Lipshultz LI.  Micromanipulation of gametes: Its role in male factor infertility.  In:     Consultant Urologist, AUA audio series, 1994.

 

8. Turek, PJ and Lue TF.  Penile Revascularization.  In: Lipshultz LI (ed): Atlas of Urologic clinics of North    America. 4: 129-142, Oct 1996

 

9.  Keeping it Simple: Collection, Preservation Techniques Enhance ICSI. Urology Times. 24: 6, 1996.

 

10.  Spotting Surprising Somnolent Sperm. Physician's Weekly. 13: 10, 1996.

 

11.  Turek PJ. What is Really Happening to Men's Sperm Counts? RESOLVE Newsletter, March 1996.

 

12. Turek PJ. Immunopathology and Infertility.  In: Infertility in the Male, 3rd ed.  Edited by  LI Lipshultz and SS Howards. Mosby Year Book, Philadelphia, 1997.

 

13. Turek, PJ  and Iriye C. Subclinical Varicocele: Fact or Fiction? Year Book in Urology. Mosby Books, Philadelphia. Vol 10: 101-120, 1997.

 

14.  Turek PJ. Male Infertility: Contemporary Practical Approaches. Practical Cases In Urology. Ed: AJ Wein. AUA Office of Education. Series 30 Course #4. 1997 .

 

15. Turek PJ and Lipshultz LI. Varicocele and Male Infertility.  In: Sciarra JJ (ed): Gynecology and Obstetrics volume 5, chapter 66.  J.B. Lippincott, 1997

 

16.  Turek PJ. Demystifying  Infertility: The Basics of the Male Evaluation. RESOLVE Newsletter, March 1997.

 

17. Turek PJ.  Commentary on Varicocele Ligation.  In: Atlas of Urologic Surgery.  Edited by Hinman F. Jr.  W. B. Saunders and Co. 1998.

 

18. Turek PJ. Seminal Vesicle and Ejaculatory Duct Surgery. In: Graham S.D. (ed): Glenn's Urologic Surgery, 5th Ed. 1998.

 

19. Turek PJ, Lowther DN, Carroll PA. Fertility Issues and Their Management in Men with Testis Cancer. Urol.Clinics N. America. 25: 517-531, 1998

 

20.  Turek PJ. Minimally Invasive Surgery for Reproductive Urology. Conference on Penile Diseases, Ediozioni Polistampa, Florence, 1998.

 

21.  Turek PJ. A Practical Guide to Sperm Banking.  RESOLVE Newsletter, July 1998.

 

22.  Turek PJ, Nagler H, Oates R, Pryor JP, Lipshultz. The Genetics of Male Infertility. Contemporary Urology. In press.

 

23.  Turek PJ. Infections, Immunity and Male Infertility. Infertility and Reprod. Cl. N. Am. 10: 1, 1999.

 

24.  Turek PJ. Male Infertility. In: Smith's Urology, 14th ed. Edited by EA Tanagho and JC McAninch.

        Appleton and Lange, Stamford, In press.

 

25.   Nudell DM and Turek PJ.  Male Infertility. In:  A Clinical Manual of Urology.  Edited by P. Hanno and A.J. Wein.  Apple-Century-Crofts, In press.

 

26.  Shamanski FL, Turek PJ, Pedersen RA. Spermatids: Clinically Useful Gametes? In: The Testis: From Stem Cell to Sperm Function.  Springer-Verlag. New York. In press.

 

27.  Turek P.J. and Reijo Pera, R.A. Genetics of Infertility. In: Encyclopedia of Genetics. Edited by Sydney Brenner and Jeffrey H. Miller, Academic Press, San Diego. In press.

 

28.  Cohen, M and Turek P.J. Vasectomy Reversal and Sperm Aspiration Techniques. RESOLVE Newsletter. October 1999.

       

 

WEB/INTERNET MANUSCRIPTS

 

1.     Turek P.J. What is Intracytoplasmic Sperm Injection? IVPCare Website. Edited by Dr. Craig Best. November 1999.

 

       

PEER REVIEWED ABSTRACTS

 

1.             Schwartz PM, Hyde CM, Turek PJ, Cadman EC and Handschumacher RE.  Altered Pharmacokinetics of       High Dose 5-Fluorouracil with Allopurinol and Analysis of Routes of 5-Fluorouracil Activation.                Proc. Am. Ass. Can. Res., May 1981.

 

2.             Turek PJ, Alpert SD, Engelman EG. Human Monoclonal Anti-T Cell Antibodies.  Clinical Research.                 33:1, 1985 and Stanford Research Symposium, 5/1985.

 

3.             Turek PJ,  Malloy TR, Cendron M, Carpiniello V, Wein AJ.  Experience with the KTP-532 Laser on    Urethral Strictures.  Am. Urol. Assoc, May 1990.

 

4.             Turek PJ, Malkowicz SB, Tomaczeski JE, Wein AJ, Peehl DM.  Human Sertoli Cell Function:                Monoclonal Antibody Analysis of Immunologic Activity. Mid-Atlantic Section, Am.Urol. Assoc.,     October 1991.

 

5.             Turek PJ, Ewalt DH, Snyder HM, Duckett JW.  Normal Epididymal Anatomy in Boys.  Am. Urol. Assoc.         Washington DC, May 1992.

 

6.             Levy JB, Baskin LS, Ewalt DH, Turek PJ, Blyth B, Snyder HM, Duckett JW.  Nonoperative      Management of Major Renal Trauma in Children.  Am. Urol. Assoc.  Washington DC, May 1992.

 

7.             Turek PJ, Stamfers D, Snyder HM, Ewalt DH, Blyth B, Huff D, Duckett JW.  The Absent          Cryptorchid Testis: Surgical Findings and their Implications for Diagnosis and Etiology. Am. Urol.            Assoc.  Washington DC, May 1992.

 

8.             Mozley PD, Turek PJ, Heyman S, Beshaim H, Snyder HM and Duckett JW.  The Prognostic Value of the          Nuclear Cystogram in Children with Reflux.  Soc. Univ. Urol. Resid., San Antonio,Texas, 1993 and              Mid-Atlantic Section, Am. Urol. Assoc. Palm Beach, Florida, September, 1993.

 

9.             Carbone D, Turek PJ, Carpiniello VL, Wein AJ and Malloy TR.  KTP-532 Laser Ablation of   Urethral Strictures: Long Term Response Rates.  Am. Urol. Assoc.  San Antonio, Texas, 1993.

 

10.          Turek PJ, Gilbaugh JH, Dunn R, Lamb DR, Lipshultz LI and Woodruff TR.  Inhibin and Activin Levels           in Normal and Infertile Males.  Am. Urol. Assoc.  Abstract #284, San Francisco, California, May 1994.

 

11.          Turek PJ, SB Malkowicz, Tomaczeski JE, Wein AJ and Peehl DM.  The Role of the Sertoli Cell in         Active Immunosuppression in the Testis.  Am. Urol. Assoc.  Abstract #326, San Francisco, California,          May 1994.

 

12.          Turek PJ, Kim M, Gilbaugh JH, Lipshultz LI.  The Clinical Characteristics of 78 Patients with Sertoli-               Cell-Only Syndrome.  Fertility and Sterility supplement, S63, 1994.

 

13.          Gilbaugh JH, Patel VR, Turek, PJ and Lipshultz LI.  Testis Biopsy Findings in Azoospermic                Patients with Markedly Elevated Serum FSH Levels.  Fertility and Sterility supplement, S63, 1994.

 

14.          Smikle CB, Tom R and Turek PJ.  Hypoosmotic Swelling can Accurately Determine the Viability        of Nonmotile Sperm.  Am. Fert. Soc.  Seattle, Washington, October 1995 and West. Sect., Am. Urol   Assoc.  Phoenix, Arizona, November 1995.

 

15.          Nguyen HT, Etzell J, and Turek PJ.  Normal Human Ejaculatory Duct Anatomy: A Study of                 Cadaveric and Fresh Specimens.  Am. Urol. Assoc.  Las Vegas, Nevada, April 1995.

 

16.          Turek PJ, Magana JO, Lipshultz LI.  Semen Parameters Before and After Transurethral Surgery for    Ejaculatory Duct Obstruction.  Am. Urol. Assoc.  Las Vegas, Nevada, April 1995.

 

17.          Hovey RM, Shinohara K, Turek PJ, Presti JC. Prostate Specific Antigen and Prostate Specific Antigen               Density in the Detection of Prostate Cancer. West. Sect., Am. Urol. Assoc.  Phoenix, Arizona, November       1995.

 

 18.         Aslam K, Turek PJ, and Nagaraju, P.  The Effects of a-adrenergic and Dopaminergic Agonists on Rat Vas      Deferens Contractility In Vivo.  Am. Urol. Assoc.  1996 annual meeting, Orlando. FL.

 

19.          Turek PJ, Aslam K, Nagaraju, P.  The Sertindole-Induced Reduction in Rat Vas Deferens Contractility is         Modulated by a-adrenergic Agonists.  Am. Urol. Assoc.  1996 annual meeting, Orlando. FL.

 

20.          Nguyen HT and Turek PJ. Variability of Seminal Vesicle Size in Healthy Men Measured by Magnetic              Resonance Imaging. Am. Urol. Assoc.  1996 annual meeting, Orlando. FL, and N. Cal. Urol Resident's     Seminar, April 27, 1996, Davis, CA.

 

20.          Smikle CB, Turek PJ, Mesiano S, Jaffe RB.  Expression of C-Kit in the Ovary and Testis of Fetal and    Adult Human and Subhuman Primates.  Surg Obstet Gynecol, 1995 Annual Meeting.

 

21.          Turek PJ and Aslam K.  Nitric Oxide Depresses Vas Deferens Contractility in the Rat In Vivo.             Journal of Andrology, Jan/Feb 1996 supplement, Abstract 116, 21st Annual Meeting, Amer. Soc. Andrology,            Minneapolis, MN.

 

22.          Tom RA, Angle MJ and Turek PJ. Protein Kinase A (PKA) May be Involved in the Platelet Activating                Factor (PAF) Induced Human Sperm Acrosome Reaction (AR).  Journal of Andrology, Jan/Feb 1996           supplement, Abstract 24, 21st Annual Meeting, Amer. Soc. Andrology, Minneapolis, MN.

 

23.          Turek P.J. and Tom R.A. An Assessment of Nuclear and DNA stability in Ejaculated Sperm with Time.          Pacific Coast Fertility Society, Indian Wells, CA, April 1996.

 

24.          Turek PJ , RA Tom. Strict (Kruger) Morphology Can Be Accurately Read on Fresh, Unstained Sperm.               Accepted Am. Soc. Reprod. Med., Annual Meeting, November 1996, Boston MA.

 

25.          Turek PJ, AK Younes and K Aslam. An In Vivo Microsurgical Animal Model of Seminal Vesicle Contractility: The Effects of Alpha-Adrenergic Agents. Am. Soc. Reprod. Med., Annual             Meeting, November 1996, Boston MA.

 

26.         Turek PJ, Cha I, Ljung BE. Testicular Systematic Fine Needle Aspiration: biopsy correlation and                        organ "mapping" for sperm in infertile men. Am. Urol. Assoc. 1997 Annual meeting, New                                                 Orleans, LA.

 

27.          Aslam K, Younes AK, Nguyen HT, and Turek PJ. Unilateral hypogastric nerve stimulation                                         induces bilateral seminal vesicle contraction.  Am. Urol. Assoc. 1997 Annual meeting, New                                         Orleans, LA.

 

28.          PJ Turek, RA Tom, RA Pederson and J Conaghan. The Mini-MESA for  Sperm Retrieval: A study       of efficacy and outcome. Pacific Coast Fertility Society. Annual Meeting, April 10-13, 1997,                Indian Wells,      CA

 

29.          PJ Turek, I Cha, BE Ljung. Fine needle aspiration "mapping" of sperm in azoospermic men.

                Pacific Coast Fertility Society. Annual Meeting, April 10-13, 1997, Indian Wells, CA.

 

30.          J Conaghan, C Givens, E Schriock, PJ Turek. Do IVF outcomes with epididymal spermatozoa              vary with male factor etiology? Pacific Coast Fertility Society. Annual Meeting, April 10-13,           1997, Indian Wells, CA.

 

31.          Nudell D., Turek PJ. The Mini-MESA for sperm retrieval: A study of urological outcomes.     Northern Calif. Urol. Soc. Annual Resident's Competitition. San Francisco, CA May 2 1997.

 

32.          PJ Turek, K Aslam and HT Nguyen. Rat seminal vesicle urodynamics: the seminal vesicle as              bladder of the reproductive tract.  Am.  Soc. Repro. Med. Annual Meeting, 1997.

 

33.          PJ Turek, D Nudell, RA Tom, RA Pederson, J Conaghan. The Mini-MESA for sperm retrieval: a          study of urological outcomes.  Am.  Soc. Repro. Med. Annual Meeting, 1997.

 

34.          PJ Turek, J Conaghan, RA Pedersen, C Givens, E Schriock. How to treat male infertility due to            Kartagener's syndrome. West Sect., Am. Urol. Assoc. Salt Lake City, Utah, Sept 1997.

 

35.          HT Nguyen, K Aslam, PJ Turek. Rat seminal vesical urodynamics: the seminal vesicle as     bladder of the reproductive tract. West Sect., Am. Urol. Assoc. Salt Lake City, Utah, Sept              1997.

 

36.          PJ Turek, J Conaghan, RA Pedersen, C Givens, E Schriock, I Cha, BM Ljung. Fine needle testis            "mapping" for sperm: a tool to locate and guide sperm retrieval for ICSI in men with non-                obstructive azoospermia. West Sect., Am. Urol. Assoc. Salt Lake City, Utah, Sept 1997.

 

37.          D Nudell, R Tom, RA Pedersen, J Conaghan, PJ Turek. The mini-MESA for sperm retrieval: a              study of urological outcomes. West Sect., Am. Urol. Assoc. Salt Lake City, Utah, Sept 1997.

 

38.          PJ Turek, MA MacInnes , N Bachtell, J Conaghan and RA Pedersen. Cryopreservation and recovery of motile, aspirated human sperm within biopsy capsules from hamster eggs. American Society of Andrology Ann Meeting, Los Angeles CA, Mar 1998 .

 

39.          PJ Turek, K Aslam and G. Benichou. Phenotype of T cell response in experimental autoimmune        orchitis. American Society of Andrology Ann Meeting, Los Angeles CA, Mar 1998.

 

40.          PJ Turek, J Conaghan, RA Pederson, C Givens, E Schriock and BM Ljung,Testis fine needle                 "mapping": a tool for sperm detection and retrieval in men with non-obstructive azoospermia.     Pacific Coast Fertility Society, Ann. Meeting, Indian Wells CA April 1998.

 

41.          DM Nudell, DM Dorfman, RA Reijo and PJ Turek. The expression of DAZ and DAZL proteins in                             human testes with normal and abnormal spermatogenesis. Am. Urol. Assoc. Annual meeting,                                    San Diego, CA May 1998.

 

42.          N Bachtell, J Conaghan and PJ Turek. Testicular sperm viability after freezing in men with non-                        obstructive azoospermia. Am. Urol. Assoc. Annual meeting, San Diego, CA May 1998.

 

43.          PJ Turek, I Cha and BE Ljung. Where are sperm located in infertile testes? A study of FNA maps       in obstructive and nonobstructive azoospermia.  Am.  Soc. Repro. Med. Annual Meeting, San Francisco, Oct 1998.

 

44.          M Meng and PJ Turek. The relationship between classic histologic pattern and sperm findings on    fine needle aspiration map in infertile testes. Am.  Soc. Repro. Med. Annual Meeting, San                 Francisco, Oct 1998.

 

45.          N. Bachtell, J. Conaghan, and P. J.Turek. The sperm hypoosmotic swelling assay for IVF and                              ICSI: Sperm viability varies with type of  tail coiling. Am.  Soc. Repro. Med. Annual Meeting,                       San Francisco, Oct 1998.

 

46.          PJ Turek, N Bachtell and J. Conaghan. The relative viability of human sperm from the testis,               epididymis and vas deferens before and after cryopreservation. Am.  Soc. Repro. Med. Annual   Meeting, San Francisco, Oct 1998.

 

47.          N. Bachtell, J. Conaghan, and P. J.Turek. The sperm hypoosmotic swelling assay for IVF and                                              ICSI: Sperm viability varies with type of  tail coiling. West Sect., Am. Urol. Assoc. Maui,                                   Hawaii, October 1998.

 

48.          PJ Turek, N. Vegesna and S S Schmidt. Pain after vasectomy: A comparison of the regular

                and no-scalpel techniques.  West Sect., Am. Urol. Assoc. Maui, Hawaii, October 1998.

 

49.          MV Meng and PJ Turek. Varicocele, cancer and cryptorchidism causing atrophy and                                                    azoospermia: Potential for fertility in 1998.  West Sect., Am. Urol. Assoc. Maui, Hawaii,                                                 October 1998.

 

50.          Lee DL, Givens CR, Schriock ED, Ryan I, Conaghan J and Turek PJ: IVF/ICSI with Epididymal                                          Sperm: Comparative Fertilization Rates with Fresh and Cryopreserved Sperm from the Same                                             Couples. Am. Urol. Assoc. Annual meeting, Dallas, TX, April 1999.

 

51.          SP Elliot, A Hernandez and PJ Turek. The Effect of a Self-Lubricated Catheter (LoFric) on                                     Sperm Viability in Patients Undergoing Electroejaculation. Am. Urol. Assoc. Annual meeting,                                          Dallas, TX, April 1999.

 

52.          DS Wu, K Shinohara and PJ Turek. Ejaculatory Duct Chromotubation as a Functional Diagnostic                     Test in Ejaculatory Duct Obstruction. Am. Urol. Assoc. Annual meeting, Dallas, TX, April 1999.

 

53.          D Nudell, RA Reijo, and PJ Turek. The Technique of Single Sperm PCR to Detect Y-Chromosome                               Microdeletions in the Ejaculates of Oligospermic Men. Am. Urol. Assoc. Annual meeting,                                             Dallas, TX, April 1999.

 

54.          MV Meng and PJ Turek. Impaired spermatogenesis in men with congenital absence of the vas                           deferens. Am.  Soc. Repro. Med. Annual Meeting, Toronto, Canada, September 1999.

 

55.          LD Black, DM Nudell, I Cha, AM Cherry and PJ Turek. Compound genetic defects as a cause of         male infertility. Am.  Soc. Repro. Med. Annual Meeting, Toronto, Canada, September 1999.

 

56.          DM Nudell, DM Lee, ED Schriock, CA Givens, PJ Turek and J Conaghan. Does embryo quality           correlate with sperm quality in male factor IVF/ICSI cases? Am.  Soc. Repro. Med. Annual            Meeting, Toronto, Canada, and West Sect., Am. Urol. Assoc. Monterey, CA.September 1999.

 

57.          PJ Turek, M Meng, I Cha, J Conaghan. Does testis injury from diagnostic fine needle aspiration          mapping affect later sperm retrieval procedures? Am.  Soc. Repro. Med. Annual Meeting,              Toronto, Canada, and West Sect., Am. Urol. Assoc. Monterey, CA. September 1999.

 

58.          MV Meng, I Cha,  PJ Turek. Correlation between fine needle aspiration cytology and testis   biopsy histology in infertile men. Am.  Soc. Repro. Med. Annual Meeting, Toronto, Canada,       and West Sect., Am. Urol. Assoc. Monterey, CA. September 1999.

 

59.          MV Meng, I Cha, PJ Turek. Varicocele, cancer and cryptorchidism causing atrophy and azoospermia: potential for fertility in 1999. Am. Soc. Repro. Med. Annual Meeting, Toronto, Canada, September 1999.

 

60.          P.J. Turek and the Saline Testis Prosthesis Study Group. Safety and effctiveness of a new saline-filled testicular prosthesis. Annual Meeting, Amer. Soc. Andrology, Boston, MA., April 2000

 

61.          P.J. Turek, M. B. Castillo, D.M. Nudell, and R. Reijo Pera. Expression of apoptosis and DNA repair genes in infertile men. Annual Meeting, Amer. Soc. Andrology, Boston, MA., April 2000.

 

 

PAST/CURRENT  SUPPORT

 

REAC Clough Fund                                                                                                                           11/94-6/97         Effort 0%

Magnetic Resonance Spectroscopy in Normal and Varicocele-Associated Testicles    $15,000

 

                Major goal of this project was to assess differences in the metabolic rates of normal

                and varicocele-associated testes to determine how varicoceles affect testis function.

 

Abbot Laboratories                                                                                                                           1/95-12/95

The Activity of the Vas Deferens and Seminal Vesicles after Systemic Administration                             Effort 0%

                of Sertindole and Mellaril                                                                                                                               $17,000

 

                The major aim of this work was to investigate the neurophysiologic mechanism

                by which antipsychotic medication inhibits ejaculation in men.                                                                                                                                     

UCSF Young Faculty Development Award                                                                                7/1/96-6/30/97  Effort 0%

Oral Tolerance and the Alteration of the Immune Response in Mouse Experimental Orchitis                  $10,000

 

                The major goal of this project was to develop a method and regimen of antigen

                feeding in micethat inhibits autoimmune orchitis, a common cause of male infertility.

 

UCSF Student Research Committee 1997 Summer Fellowship                                            5/97-8/97           Effort 0%    

Sperm Viability in the Reproductive Tract of Infertile Men. (Nathan Bachtell BS)         $2,250

 

                The major goal of this project was to asess how sperm motility and viability change

                with progression through the ducts of the human male reproductive tract. 

                                                                                                                                                                 

The California Urology Foundation                                                                                             1/1/98-1/1/99 Effort 0%    

Y-Chromosome Deletion Analysis Of Single Sperm from Oligospermic Men                                                $10,000

                 (co-PI Renee Reijo PhD)

 

                The major goal of this project is to develop molecular genetic methods

                to assess for the presence of Y chromosome microdeletions that are

                associated with defective spermatogenesis in the sperm of infertile men

 

Bank of America-Giannini Foundation Fellowship                                                                6/98-6/99           Effort 0% 

Y Chromosome Deletion Analysis of Single Sperm from Oligospermic Men (D. Nudell MD)                    $30,000

 

                The major goal of this project is to develop molecular genetic methods that would allow the

                evaluation of individual sperm chromosomes for genetic defects associated with infertility.

 

EPA Grant. "Semen Abnormalities in Patients Undergoing Radiation Therapy."   2/98-8/00                Effort 5%

                (P.I. Paul Turek M.D., Co-investigator: Ana Maria Osorio M.D. M.P.H)                                          $100,000

               

                The major goal of this project is to assess the acute effects of ionizing radiation on

                sperm chromosomal aneuploidy and DNA structure.

 

UC Clinical-laboratory Collaboration Grant                                                                            10/1/98-9/30/00

Identification and Characterization of Quantitative and Qualitative Defects in Expression of                 Effort 0%

        Fertility Genes in Infertile Men Using cDNA Microarrays (co-PIs: R. Reijo PhD;                                    $175,000/yr

                A. Wyrobek PhD and R.Pedersen PhD).

               

                The major goal of this project is to construct cDNA microarrays to monitor the expression

                of male fertility genes in men with infertility.

 

NICHD-Program Project on the Epidemiology of Infertility                                                  6/99-6/2003           5% effort

                Poor Obstetric and Pediatric Outcomes After Infertility                                                                         $1,500,000

                (Co-investigator with P.I. Mary Croughan-Minihane Ph.D)                                                                

 

                The major goals of this study is to assess the medical outcomes of children

                conceived through the use of assisted reproductive technologies for either

                male or female infertility

 

UCSF-Stanford Healthcare Enterprise Fund.                                                                             12/98-11/99       0% Effort

                Program in the Genetics of Infertility (PROGENI)                                                                                    $50,000

               

                The  major goal of this clinical and research program is to diagnose,

                counsel and treat genetic causes of infertility

 

Chancellor's Innovations in Basic Science Award                                                                   10/98-10/99       0% Effort

                Meiotic Arrest and Defects in the Recombination and DNA Repair Pathways                              $40,000

                in Infertile Men. (Collaborator with P.I. Renee Reijo PhD)                                                                    

               

                This work seeks to investigate the molecular genetic relationship between

                human male infertility and defects in DNA repair pathways that have

                associations with the development of malignancy. 

 

The California Urology Foundation                                                                                    1/1/99-1/1/00           0% Effort    

Defects in DNA Recombination and Repair Pathways in Infertile Men.                                                          $5,000

                 (co-PI Renee Reijo PhD)

 

                The major goal of this project is to investigate the phenomenon of microsatellite

                instability and defective DNA recombination and its relationship to male infertility.

 

NIH RO1HD37095

The DAZ Genes and Early Germ Cell Development in Humans.                              7/1/99-6/30/04         5% effort

                (Collaborator with P.I. Renee Reijo Ph.D)                                                                                     $909,864           

                The major goal of this project is to identify and characterize several putative genes

                that may play a role in the process of meiosis, spermatogenesis  and male infertility.

 

 

GRANTS SUBMITTED

 

NIH U54-Center Project Grant (Robert Jaffe MD, Richard Weiner PhD P.I.'s) 01/01/00-12/31/04        5% Effort            

Genetic, Molecular and Cellular Basis of Infertility.                                                                                                $1,250,000          (co-investigator; P.I.: R. Reijo PhD)

 

                The major goal of this study is to pursue the elucidation of genes that

                may regulate meiosis and therefore fertility in the human male.

 

NIH RO1                                                                                                                                      4/01/00-3/31/04      5% effort

Genetic Analysis of Meiosis in Men and Risks Associated with ICSI.                                                               $1,612,450

(Collaborator with P.I. Rene Reijo Ph.D)

 

                The major goals of this project are to determine if defects in DNA repair and recombination

                cause infertility in men, to identify and characterize genes that cause meiotic arrest in men,

and to assess genetic risks in children conceived via intracytoplasmic sperm injection from men with meiotic arrest. This project overlaps the U-54 project, and will not be accepted if the U-54 grant is funded.